Best Berberine Supplement for Weight Loss: What to Look For

Best Berberine Supplement for Weight Loss: What to Look For

, by Sara McKinney

Not a plant and not a plant part but a chemical compound extracted from Berberis shrubs, berberine is increasingly popular for a wide range of health benefits. Those benefits include lower cholesterol, lower blood sugar, and weight loss, but they don’t stop there. In this article, discover what berberine is, how to use berberine for weight loss, and the best berberine supplement for weight loss.

What is Berberine?

Berberine is a bitter, yellow compound extracted from shrubs including barberry and Oregon grape. Classified as an alkaloid, berberine is a chemically active supplement that has been used for thousands of years in traditional Chinese medicine. Those traditional uses include the treatment of infections, inflammation, pain, and gastrointestinal issues. In fact, the oldest use of berberine dates all the way back to 650 BC Assyria, where it was used as a blood purifier. 

Modern studies tend to focus on berberine’s effectiveness as a heart health and weight loss supplement. This is largely due to berberine’s activation of a key metabolic enzyme called AMP-activated protein kinase (AMPK). AMPK plays critical roles in a number of metabolic processes including cell growth, lipid metabolism, glucose metabolism, and autophagy. Berberine’s effectiveness as a metabolism support supplement has been demonstrated across hundreds of studies. 

Best Berberine Supplement Benefits

The best berberine supplement benefits include: 

  • Weight loss
  • Lower cholesterol
  • Lower blood sugar
  • Lower triglycerides
  • Lower blood pressure
  • Improved cognitive health
  • Reduced inflammation
  • Supports healthy gut bacteria
  • Antimicrobial support
  • PMOS/PCOS relief

Berberine for Weight Loss

One of the most popular uses of berberine is as a weight loss aid. Often called “nature’s Ozempic,” berberine has a powerful effect on the body’s metabolism, regulating blood sugar, glucose metabolism, and lipid metabolism through the activity of the AMPK enzyme. 

Studies suggest that berberine can boost weight loss. In one 2012 study, participants diagnosed with obesity took 500mg of berberine three times daily for 12 weeks, yielding an average body fat loss of 3.6%. Additionally, participants saw a significant reduction in triglycerides (23%) and cholesterol (12.2%).

A 2020 review of 12 studies found that regular berberine supplementation produced significant reductions in body weight, BMI, belly fat, and critical inflammation markers. And yet another study, published in 2018, found that berberine may inhibit the growth of fat cells. 

How to Dose Berberine for Weight Loss

Berberine has proven an effective supplement for weight loss. However, because of its short half-life (several hours) it’s ideal to split doses throughout the day. Ideally, 500mg per dose taken 2-3 times a day. 

Berberine is also best taken with meals. Not only does this limit stomach-related side effects like cramps and nausea, taking berberine before a meal can help manage post-meal blood sugar. Finally, taking berberine with probiotics or fermented foods can increase its heart health benefits.

Where to Buy Berberine Supplements

Wondering where you can buy the best berberine supplements? MediHerb Berberine Active contains 200mg of active berberine sourced from high-quality Phellodendron bark. Phellodendron has been traditionally used in Chinese medicine to cleanse and heal the lower intestinal tract. 

This maximizes the health impacts on the microbiome, encouraging the growth of healthy probiotic organisms and cleansing unwanted microorganisms, all while boosting weight loss. Buy MediHerb Berberine Active in our shop.


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